AGE REVERSAL WITH

GHK-Cu Copper Peptide

The human peptide GHK (glycyl-l-histidyl-l-lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive.

Content courtesy: reverseagingwithghk.com

SKIN & HAIR

GHK was first studied for wound healing (1983+) and later for its effects on skin and hair. In many controlled, peer-reviewed published articles, GHK was found to:

Tightened and Loose Skin
and thicken older skin.

Repaired
protective skin barrier proteins.

Improved
skin firmness, elasticity, and clarity.

Reduced fine lines

depth of wrinkles, and overall appearance.

Smoothed

rough skin.

Reduced Photodamage

mottled hyperpigmentation, skin spots and lesions.

Improved

overall appearance.

Protected skin cells
from UV radiation.

Increased Hair Growth

and thickness, enlarge hair follicle size.

Accelerated Wound Healing
but better when used in liposomes due to its sensitivity to carboxypeptidase breakdown effects.

ANTI-CANCER ACTIONS

Topped 1,309 bioactive compounds

as the Broad Institute computer recommended molecule for the treatment of human METASTATIC COLON CANCER

GHK inhibited NFKB p65

which is believed to promote cancer growth.

GHK, at 1 nanomolar
reset the PROGRAMMED CELL DEATH system in human cancer cells (human neuroblastoma, leukemia, and breast cancer) but did not affect healthy cells.

Repaired Damaged DNA

at cellular level at 1 nanomolar (47 genes up, 5 genes down).

GHK-copper plus

ascorbic acid suppressed a sarcoma in mice.

GHK-copper
induced cell differentiation.

Reset 84 genes

to growth inhibition or cancer inhibition.

LUNG PROTECTION

Topped 1,309 bioactive compounds
as Broad Institute computer recommended molecule for treatment of chronic obstructive obstructive pulmonary disease. Restored healthy function in COPD affected cells at 10 nanomolar.

Protected Lung Cells
from damage by both bleomycin and lipopolysaccharide-induced

In fetal lung cells

GHK-Cu (at concentrations of 0.1, 1.0, and 10 nanomolar) produced dose-response changes in 329 human fetal lung genes of the extracellular matrix.

ANTIOXIDANT / ANTI-INFLAMMATORY

Increased SOD1 Activity

Suppressed toxic products of lipid oxidation alpha,beta-4-hydroxy-trans-2-noneal and acrolein, peroxyl radicals, hydroxyl radicals, p38 MAPK, IL-6, IL-17, TNF alpha, and strongly suppressed NFKB, a molecule which is believed to be a primary cause of many diseases of aging.

Completely Blocked CU2+ Oxidation

of low density lipoproteins while SOD1 gave only 20% blocking.

Blocked Release of

Oxidizing iron from ferritin.

BRAIN & NERVES

Altered expression of human genes

important in neuron function by 50%, plus or minus, with 408 UP and 230 DOWN.

Induced strong Anti-Anxiety & Anti-Aggression

effects in rats within 12 minutes at a weight equivalent of 35 micrograms in 70 Kg humans.

Induced Anti-Pain Activity

in rats within 12 minutes.

Alleviated neuronal apoptosis

due to Intracerebral hemorrhage.

Now used clinically in humans

for the treatment of damaged spinal segments in the neck. Treatment was for 20 days with a daily injection of 0.25 mg GHK-Cu into the skin around the damaged area. The cost of GHK-Cu is about $0.01 a milligram.

STEM CELLS & OTHER ACTIONS

Caused adult MCS Stem Cells

to produce more growth factors, increased stem cell differentiation.

Enhanced activity of

alginate hydrogels for human cord blood MCS Stem Cell Ostegenesis.

ADDITIONAL ACTIONS OF GHK

Increased the healing of

many tissues including skin, stomach, intestine lining, bone tissue.

Strongly chemo-attracted

capillary cells, mast cells, and macrophages.

Strongly activated genes of

the Ubiquitin proteasome system used for cell cleansing. (41 genes up, 1 gene down).

Blocked Locked Cortisone's

anti-regeneration effects.

Suppressed the Insulin

and insulin-like system that reduces lifespan in roundworms.

Reduced Fibrinogen synthesis
Fibrinogen levels are the top predictor of cardiovascular heart disease.

Increased Myostatin

gene expression 9.4 fold. Myostatin inhibits heart failure.

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