AGE REVERSAL WITH
GHK-Cu Copper Peptide
The human peptide GHK (glycyl-l-histidyl-l-lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive.
Content courtesy: reverseagingwithghk.com
SKIN & HAIR
GHK was first studied for wound healing (1983+) and later for its effects on skin and hair. In many controlled, peer-reviewed published articles, GHK was found to:
Tightened and Loose Skin
and thicken older skin.
protective skin barrier proteins.
skin firmness, elasticity, and clarity.
Reduced fine lines
depth of wrinkles, and overall appearance.
mottled hyperpigmentation, skin spots and lesions.
Protected skin cells
from UV radiation.
Increased Hair Growth
and thickness, enlarge hair follicle size.
Accelerated Wound Healing
but better when used in liposomes due to its sensitivity to carboxypeptidase breakdown effects.
Topped 1,309 bioactive compounds
as the Broad Institute computer recommended molecule for the treatment of human METASTATIC COLON CANCER
GHK inhibited NFKB p65
which is believed to promote cancer growth.
GHK, at 1 nanomolar
reset the PROGRAMMED CELL DEATH system in human cancer cells (human neuroblastoma, leukemia, and breast cancer) but did not affect healthy cells.
Repaired Damaged DNA
at cellular level at 1 nanomolar (47 genes up, 5 genes down).
ascorbic acid suppressed a sarcoma in mice.
induced cell differentiation.
Reset 84 genes
to growth inhibition or cancer inhibition.
Topped 1,309 bioactive compounds
as Broad Institute computer recommended molecule for treatment of chronic obstructive obstructive pulmonary disease. Restored healthy function in COPD affected cells at 10 nanomolar.
Protected Lung Cells
from damage by both bleomycin and lipopolysaccharide-induced
In fetal lung cells
GHK-Cu (at concentrations of 0.1, 1.0, and 10 nanomolar) produced dose-response changes in 329 human fetal lung genes of the extracellular matrix.
ANTIOXIDANT / ANTI-INFLAMMATORY
Increased SOD1 Activity
Suppressed toxic products of lipid oxidation alpha,beta-4-hydroxy-trans-2-noneal and acrolein, peroxyl radicals, hydroxyl radicals, p38 MAPK, IL-6, IL-17, TNF alpha, and strongly suppressed NFKB, a molecule which is believed to be a primary cause of many diseases of aging.
Completely Blocked CU2+ Oxidation
of low density lipoproteins while SOD1 gave only 20% blocking.
Blocked Release of
Oxidizing iron from ferritin.
BRAIN & NERVES
Altered expression of human genes
important in neuron function by 50%, plus or minus, with 408 UP and 230 DOWN.
Induced strong Anti-Anxiety & Anti-Aggression
effects in rats within 12 minutes at a weight equivalent of 35 micrograms in 70 Kg humans.
Induced Anti-Pain Activity
in rats within 12 minutes.
Alleviated neuronal apoptosis
due to Intracerebral hemorrhage.
Now used clinically in humans
for the treatment of damaged spinal segments in the neck. Treatment was for 20 days with a daily injection of 0.25 mg GHK-Cu into the skin around the damaged area. The cost of GHK-Cu is about $0.01 a milligram.
STEM CELLS & OTHER ACTIONS
Caused adult MCS Stem Cells
to produce more growth factors, increased stem cell differentiation.
Enhanced activity of
alginate hydrogels for human cord blood MCS Stem Cell Ostegenesis.
ADDITIONAL ACTIONS OF GHK
Increased the healing of
many tissues including skin, stomach, intestine lining, bone tissue.
capillary cells, mast cells, and macrophages.
Strongly activated genes of
the Ubiquitin proteasome system used for cell cleansing. (41 genes up, 1 gene down).
Blocked Locked Cortisone's
Suppressed the Insulin
and insulin-like system that reduces lifespan in roundworms.
Reduced Fibrinogen synthesis
Fibrinogen levels are the top predictor of cardiovascular heart disease.
gene expression 9.4 fold. Myostatin inhibits heart failure.
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